Ibutilide Fumarate

CHEMBL2355456 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

885.2 g/mol

LogP

—

Phase

4

This fumarate salt of ibutilide is the intravenous formulation used in hospitals to convert acute-onset atrial fibrillation or flutter to normal heart rhythm. It acts by prolonging the cardiac repolarization phase, which helps restore synchronized electrical activity. Continuous ECG monitoring is required during and after infusion due to proarrhythmic risk.

Peso Molecular

885,2000 g/mol

TPSA

231,00 Å²

Áreas Terapêuticas

Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.CCCCCCCN(CC)CCCC(O)c1ccc(NS(C)(=O)=O)cc1.O=C(O)/C=C/C(=O)O

InChI

InChI=1S/2C20H36N2O3S.C4H4O4/c2*1-4-6-7-8-9-16-22(5-2)17-10-11-20(23)18-12-14-19(15-13-18)21-26(3,24)25;5-3(6)1-2-4(7)8/h2*12-15,20-21,23H,4-11,16-17H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;;2-1+

Molecular Formula

C44H76N4O10S2

HBD / HBA

6 / 14

Ligações Rotacionáveis

30

Átomos Pesados

60

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This fumarate salt of ibutilide is the intravenous formulation used in hospitals to convert acute-onset atrial fibrillation or flutter to normal heart rhythm. It acts by prolonging the cardiac repolarization phase, which helps restore synchronized electrical activity. Continuous ECG monitoring is required during and after infusion due to proarrhythmic risk.

Yes, Ibutilide Fumarate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2355456. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5281065. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Estrutura

Dados Rápidos

Fórmula: C44H76N4O10S2
Sinônimos: 1

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.