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Imipenem Anhydrous

CHEMBL148 Phase 4 Aprovado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
299.4 g/mol
LogP
-0.7
Phase
4

This anhydrous form of imipenem is the active component used in combination antibiotic preparations (typically with cilastatin) to treat severe gram-negative and gram-positive bacterial infections. It works by binding to penicillin-binding proteins to inhibit bacterial cell wall construction. The anhydrous form refers to the compound without bound water molecules used in formulation.

Peso Molecular

299,3500 g/mol

LogP

-0,70

TPSA

142,00 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Infectious Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(SCCNC=N)C[C@H]12

                

                

                
                

                    
InChI

                    
InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C12H17N3O4S

                    

                    
                    

                        
HBD / HBA

                        
3 / 6

                    

                    
                    

                        
Ligações Rotacionáveis

                        
6

                    

                    
                    
                    

                        
Átomos Pesados

                        
20

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
This anhydrous form of imipenem is the active component used in combination antibiotic preparations (typically with cilastatin) to treat severe gram-negative and gram-positive bacterial infections. It works by binding to penicillin-binding proteins to inhibit bacterial cell wall construction. The anhydrous form refers to the compound without bound water molecules used in formulation.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Imipenem Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL148.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 104838.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.