Maprotiline

CHEMBL21731 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

277.4 g/mol

LogP

4.6

Phase

4

A tetracyclic antidepressant that works by blocking the reuptake of norepinephrine in the brain, used to treat major depressive disorder and anxiety associated with depression. It takes several weeks of regular use to achieve its full therapeutic effect.

Peso Molecular

277,4000 g/mol

LogP

4,60

TPSA

12,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Schizophrenia Generalized Anxiety Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CNCCCC12CCC(c3ccccc31)c1ccccc12

InChI

InChI=1S/C20H23N/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20/h2-5,7-10,15,21H,6,11-14H2,1H3

Molecular Formula

C20H23N

HBD / HBA

1 / 1

Ligações Rotacionáveis

4

Átomos Pesados

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A tetracyclic antidepressant that works by blocking the reuptake of norepinephrine in the brain, used to treat major depressive disorder and anxiety associated with depression. It takes several weeks of regular use to achieve its full therapeutic effect.

Yes, Maprotiline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL21731. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4011. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Procura informações acessíveis para o paciente?

Maprotiline no PillFYI

Estrutura

Dados Rápidos

Fórmula: C20H23N

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.