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Methyl Salicylate

CHEMBL108545 Phase 4 Aprovado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
152.2 g/mol
LogP
2.3
Phase
4

This compound found naturally in wintergreen plants is used topically as a counterirritant to relieve minor muscle and joint pain by creating a warming sensation that distracts from deeper pain and mildly increases blood flow to the area. It is a common ingredient in muscle rubs and liniments, but must be used carefully as it can be toxic if absorbed through the skin in large amounts.

Peso Molecular

152,1500 g/mol

LogP

2,30

TPSA

46,50 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Pain Management Non-Small Cell Lung Cancer Obesity Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Prostate Cancer Colorectal Cancer

Mecanismo de Ação

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mecanismo

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Estrutura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COC(=O)c1ccccc1O

                

                

                
                

                    
InChI

                    
InChI=1S/C8H8O3/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5,9H,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H8O3

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
Ligações Rotacionáveis

                        
2

                    

                    
                    
                    

                        
Átomos Pesados

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
This compound found naturally in wintergreen plants is used topically as a counterirritant to relieve minor muscle and joint pain by creating a warming sensation that distracts from deeper pain and mildly increases blood flow to the area. It is a common ingredient in muscle rubs and liniments, but must be used carefully as it can be toxic if absorbed through the skin in large amounts.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Methyl Salicylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL108545.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4133.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.