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Moxifloxacin

CHEMBL32 Phase 4 Aprovado Small molecule
Half-Life
12 hours
Bioavailability
—
Protein Binding
—
Molecular Weight
401.4 g/mol
LogP
0.6
Phase
4

This broad-spectrum antibiotic belongs to the fluoroquinolone class and is used to treat bacterial infections of the lungs, sinuses, skin, and abdomen. It works by preventing bacteria from replicating their DNA, effectively stopping the infection from spreading.

Peso Molecular

401,4350 g/mol

LogP

0,60

TPSA

82,10 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Endometriosis Cardiovascular Disease Age-Related Macular Degeneration Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Osteoporosis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Epilepsy Migraine Schizophrenia Infectious Disease Systemic Lupus Erythematosus Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Gout Chronic Pain Malaria HIV/AIDS Hepatitis C Tuberculosis Heart Failure Atrial Fibrillation Prostate Cancer Colorectal Cancer Leukemia

Classes de Medicamentos

J — J - Antiinfectives for Systemic Use

Mecanismo de Ação

Fourth-generation fluoroquinolone inhibiting DNA gyrase and topoisomerase IV with enhanced anaerobic activity.

Pharmacokinetics (PK)

Half-Life 12 hours

Pharmacodynamics (PD)

Mecanismo

Fourth-generation fluoroquinolone inhibiting DNA gyrase and topoisomerase IV with enhanced anaerobic activity.

Estrutura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12

                

                

                
                

                    
InChI

                    
InChI=1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C21H24FN3O4

                    

                    
                    

                        
HBD / HBA

                        
2 / 8

                    

                    
                    

                        
Ligações Rotacionáveis

                        
4

                    

                    
                    
                    

                        
Átomos Pesados

                        
29

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
This broad-spectrum antibiotic belongs to the fluoroquinolone class and is used to treat bacterial infections of the lungs, sinuses, skin, and abdomen. It works by preventing bacteria from replicating their DNA, effectively stopping the infection from spreading.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Fourth-generation fluoroquinolone inhibiting DNA gyrase and topoisomerase IV with enhanced anaerobic activity.

                        

                    

                    

                    
                    

                        
                        

                            
Key pharmacokinetic parameters for Moxifloxacin: Half-life: 12 hours.

                        

                    

                    

                    

                        
                        

                            
Yes, Moxifloxacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            
            

                
Related Drugs


                
                

                    
Same Drug Class

                    

                        
                        
                            Amoxicillin
                            Small molecule
                        
                        
                        
                            Azithromycin
                            Small molecule
                        
                        
                        
                            Ciprofloxacin
                            Small molecule
                        
                        
                        
                            Doxycycline
                            Small molecule
                        
                        
                    

                

                

                
            

            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL32.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 152946.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.