Nafcillin

CHEMBL1443 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

414.5 g/mol

LogP

2.9

Phase

4

This penicillin-type antibiotic is used to treat serious bacterial infections caused by staphylococci, including those resistant to other penicillins. It is typically given by injection in a hospital setting and works by disrupting the bacteria's ability to build their cell walls.

Peso Molecular

414,5000 g/mol

LogP

2,90

TPSA

121,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Pain Management Epilepsy Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Insomnia Chronic Kidney Disease Hypertension Chronic Pain Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CCOc1ccc2ccccc2c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O

InChI

InChI=1S/C21H22N2O5S/c1-4-28-13-10-9-11-7-5-6-8-12(11)14(13)17(24)22-15-18(25)23-16(20(26)27)21(2,3)29-19(15)23/h5-10,15-16,19H,4H2,1-3H3,(H,22,24)(H,26,27)/t15-,16+,19-/m1/s1

Molecular Formula

C21H22N2O5S

HBD / HBA

2 / 6

Ligações Rotacionáveis

5

Átomos Pesados

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This penicillin-type antibiotic is used to treat serious bacterial infections caused by staphylococci, including those resistant to other penicillins. It is typically given by injection in a hospital setting and works by disrupting the bacteria's ability to build their cell walls.

Yes, Nafcillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1443. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 8982. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Estrutura

Dados Rápidos

Fórmula: C21H22N2O5S

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.