Netilmicin
This aminoglycoside antibiotic is given by injection to treat serious bacterial infections, including those caused by bacteria resistant to gentamicin. It works by binding to bacterial ribosomes and disrupting protein synthesis, killing the bacteria.
Peso Molecular
475,6000 g/mol
LogP
-4,20
TPSA
200,00 Ų
Regra dos 5 de Lipinski
Reprovado
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O
InChI
InChI=1S/C21H41N5O7/c1-4-26-13-7-12(24)16(32-19-11(23)6-5-10(8-22)31-19)14(27)17(13)33-20-15(28)18(25-3)21(2,29)9-30-20/h5,11-20,25-29H,4,6-9,22-24H2,1-3H3/t11-,12+,13-,14+,15-,16-,17+,18-,19-,20-,21+/m1/s1
Molecular Formula
C21H41N5O7
HBD / HBA
8 / 12
Ligações Rotacionáveis
8
Átomos Pesados
33
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
This aminoglycoside antibiotic is given by injection to treat serious bacterial infections, including those caused by bacteria resistant to gentamicin. It works by binding to bacterial ribosomes and disrupting protein synthesis, killing the bacteria.
Yes, Netilmicin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1572. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 441306. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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