Omacetaxine Mepesuccinate

CHEMBL46286 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

545.6 g/mol

LogP

0.8

Phase

4

A protein synthesis inhibitor for CML that has not responded to other targeted therapies.

Peso Molecular

545,6000 g/mol

LogP

0,80

TPSA

124,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Lymphoma Prostate Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

COC(=O)C[C@](O)(CCCC(C)(C)O)C(=O)O[C@@H]1C(OC)=C[C@]23CCCN2CCc2cc4c(cc2[C@H]13)OCO4

InChI

InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1

Molecular Formula

C29H39NO9

HBD / HBA

2 / 10

Ligações Rotacionáveis

11

Átomos Pesados

39

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A protein synthesis inhibitor for CML that has not responded to other targeted therapies.

Yes, Omacetaxine Mepesuccinate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL46286. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 285033. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Estrutura

Dados Rápidos

Fórmula: C29H39NO9

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.