Peficitinib

CHEMBL3137308 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

326.4 g/mol

LogP

1.9

Phase

4

A JAK inhibitor taken orally to treat rheumatoid arthritis by blocking the signaling pathways that drive joint inflammation and damage. It provides an oral alternative to injectable biologic therapies for patients who need disease-modifying treatment.

Peso Molecular

326,4000 g/mol

LogP

1,90

TPSA

104,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Rheumatoid Arthritis Psoriasis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

NC(=O)c1cnc2[nH]ccc2c1N[C@@H]1[C@@H]2CC3C[C@H]1C[C@@](O)(C3)C2

InChI

InChI=1S/C18H22N4O2/c19-16(23)13-8-21-17-12(1-2-20-17)15(13)22-14-10-3-9-4-11(14)7-18(24,5-9)6-10/h1-2,8-11,14,24H,3-7H2,(H2,19,23)(H2,20,21,22)/t9?,10-,11+,14-,18-

Molecular Formula

C18H22N4O2

HBD / HBA

4 / 4

Ligações Rotacionáveis

3

Átomos Pesados

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A JAK inhibitor taken orally to treat rheumatoid arthritis by blocking the signaling pathways that drive joint inflammation and damage. It provides an oral alternative to injectable biologic therapies for patients who need disease-modifying treatment.

Yes, Peficitinib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3137308. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 57928403. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Estrutura

Dados Rápidos

Fórmula: C18H22N4O2

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.