Pemetrexed Tromethamine

CHEMBL3989962 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

705.7 g/mol

LogP

—

Phase

4

A tromethamine form of pemetrexed with the same therapeutic properties. This chemotherapy drug stops cancer cells from making DNA and RNA, used primarily for lung cancer and mesothelioma.

Peso Molecular

705,7000 g/mol

TPSA

362,00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

NC(CO)(CO)CO.NC(CO)(CO)CO.Nc1nc(=O)c2c(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)c[nH]c2[nH]1.O.O

InChI

InChI=1S/C20H21N5O6.2C4H11NO3.2H2O/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27;2*5-4(1-6,2-7)3-8;;/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29);2*6-8H,1-3,5H2;2*1H2/t13-;;;;/m0..../s1

Molecular Formula

C28H47N7O14

HBD / HBA

16 / 17

Ligações Rotacionáveis

15

Átomos Pesados

49

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A tromethamine form of pemetrexed with the same therapeutic properties. This chemotherapy drug stops cancer cells from making DNA and RNA, used primarily for lung cancer and mesothelioma.

Yes, Pemetrexed Tromethamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989962. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 135565678. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estrutura

Dados Rápidos

Fórmula: C28H47N7O14

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.