Pirfenidone

CHEMBL1256391 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

185.2 g/mol

LogP

1.9

Phase

4

Used to slow the progression of idiopathic pulmonary fibrosis, a serious lung disease that causes the lung tissue to become scarred and stiff, making it increasingly difficult to breathe. It works by reducing inflammation and the build-up of scar tissue in the lungs.

Peso Molecular

185,2200 g/mol

LogP

1,90

TPSA

20,30 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Respiratory Disease Non-Small Cell Lung Cancer Rheumatoid Arthritis Chronic Obstructive Pulmonary Disease Multiple Sclerosis Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Type 2 Diabetes Breast Cancer Hepatitis C Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure

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SMILES

Cc1ccc(=O)n(-c2ccccc2)c1

InChI

InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3

Molecular Formula

C12H11NO

HBD / HBA

- / 1

Ligações Rotacionáveis

1

Átomos Pesados

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Used to slow the progression of idiopathic pulmonary fibrosis, a serious lung disease that causes the lung tissue to become scarred and stiff, making it increasingly difficult to breathe. It works by reducing inflammation and the build-up of scar tissue in the lungs.

Yes, Pirfenidone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1256391. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 40632. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Estrutura

Dados Rápidos

Fórmula: C12H11NO
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.