Propafenone

CHEMBL631 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

341.4 g/mol

LogP

3.3

Phase

4

Used to treat certain serious abnormal heart rhythms, including atrial fibrillation and other supraventricular arrhythmias, by slowing electrical conduction in the heart to restore and maintain a normal rhythm. It is reserved for people without structural heart disease due to the risk of serious side effects in those with underlying heart conditions.

Peso Molecular

341,4000 g/mol

LogP

3,30

TPSA

58,60 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Cardiovascular Disease Stroke Hypertension Heart Failure Atrial Fibrillation

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1

InChI

InChI=1S/C21H27NO3/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17/h3-11,18,22-23H,2,12-16H2,1H3

Molecular Formula

C21H27NO3

HBD / HBA

2 / 4

Ligações Rotacionáveis

11

Átomos Pesados

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Used to treat certain serious abnormal heart rhythms, including atrial fibrillation and other supraventricular arrhythmias, by slowing electrical conduction in the heart to restore and maintain a normal rhythm. It is reserved for people without structural heart disease due to the risk of serious side effects in those with underlying heart conditions.

Yes, Propafenone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL631. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4932. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Propafenone no PillFYI

Estrutura

Dados Rápidos

Fórmula: C21H27NO3
Sinônimos: 2

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.