Quazepam

CHEMBL1200472 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

386.8 g/mol

LogP

4.0

Phase

4

Quazepam is a long-acting benzodiazepine hypnotic that selectively binds to the omega-1 (BZ1) benzodiazepine receptor subtype, enhancing GABA-A mediated inhibitory neurotransmission to reduce sleep onset latency and increase total sleep time. It is indicated for the short-term treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and early morning awakenings.

Peso Molecular

386,8000 g/mol

LogP

4,00

TPSA

47,70 Å²

Regra dos 5 de Lipinski

Aprovado

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

Fc1ccccc1C1=NCC(=S)N(CC(F)(F)F)c2ccc(Cl)cc21

InChI

InChI=1S/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2

Molecular Formula

C17H11ClF4N2S

HBD / HBA

- / 6

Ligações Rotacionáveis

2

Átomos Pesados

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Quazepam is a long-acting benzodiazepine hypnotic that selectively binds to the omega-1 (BZ1) benzodiazepine receptor subtype, enhancing GABA-A mediated inhibitory neurotransmission to reduce sleep onset latency and increase total sleep time. It is indicated for the short-term treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and early morning awakenings.

Yes, Quazepam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200472. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4999. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Procura informações acessíveis para o paciente?

Quazepam no PillFYI

Estrutura

Dados Rápidos

Fórmula: C17H11ClF4N2S

Links Externos

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.