Tenapanor Hydrochloride

CHEMBL3301627 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

1218.0 g/mol

LogP

—

Phase

4

Tenapanor hydrochloride is the hydrochloride salt form of tenapanor, an NHE3 inhibitor that reduces intestinal sodium and phosphate absorption. See tenapanor for complete pharmacological details. This salt formulation is used in approved oral tablet preparations for IBS-C and hyperphosphatemia in dialysis patients.

Peso Molecular

1218,0000 g/mol

TPSA

235,00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CN1Cc2c(Cl)cc(Cl)cc2[C@H](c2cccc(S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)c3cccc([C@@H]4CN(C)Cc5c(Cl)cc(Cl)cc54)c3)c2)C1.Cl.Cl

InChI

InChI=1S/C50H66Cl4N8O10S2.2ClH/c1-61-31-43(41-27-37(51)29-47(53)45(41)33-61)35-7-5-9-39(25-35)73(65,66)59-15-19-71-23-21-69-17-13-57-49(63)55-11-3-4-12-56-50(64)58-14-18-70-22-24-72-20-16-60-74(67,68)40-10-6-8-36(26-40)44-32-62(2)34-46-42(44)28-38(52)30-48(46)54;;/h5-10,25-30,43-44,59-60H,3-4,11-24,31-34H2,1-2H3,(H2,55,57,63)(H2,56,58,64);2*1H/t43-,44-;;/m0../s1

Molecular Formula

C50H68Cl6N8O10S2

HBD / HBA

8 / 14

Ligações Rotacionáveis

29

Átomos Pesados

76

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Tenapanor hydrochloride is the hydrochloride salt form of tenapanor, an NHE3 inhibitor that reduces intestinal sodium and phosphate absorption. See tenapanor for complete pharmacological details. This salt formulation is used in approved oral tablet preparations for IBS-C and hyperphosphatemia in dialysis patients.

Yes, Tenapanor Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3301627. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 78131177. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Tenapanor Hydrochloride no PillFYI

Estrutura

Dados Rápidos

Fórmula: C50H68Cl6N8O10S2
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.