Tetramethrin
Tetramethrin is a synthetic pyrethroid insecticide that acts on insect voltage-gated sodium channels, holding them open and causing repetitive nerve firing, leading to paralysis and death of insects. It is used in household and agricultural insecticide formulations for control of flies, mosquitoes, cockroaches, and other pests, often in combination with synergists such as piperonyl butoxide. Its rapid knockdown effect and relatively low mammalian toxicity make it widely used in pest control applications.
Peso Molecular
331,4000 g/mol
LogP
4,70
TPSA
63,70 Ų
Regra dos 5 de Lipinski
Aprovado
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CC(C)=CC1C(C(=O)OCN2C(=O)C3=C(CCCC3)C2=O)C1(C)C
InChI
InChI=1S/C19H25NO4/c1-11(2)9-14-15(19(14,3)4)18(23)24-10-20-16(21)12-7-5-6-8-13(12)17(20)22/h9,14-15H,5-8,10H2,1-4H3
Molecular Formula
C19H25NO4
HBD / HBA
- / 4
Ligações Rotacionáveis
5
Átomos Pesados
24
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
Tetramethrin is a synthetic pyrethroid insecticide that acts on insect voltage-gated sodium channels, holding them open and causing repetitive nerve firing, leading to paralysis and death of insects. It is used in household and agricultural insecticide formulations for control of flies, mosquitoes, cockroaches, and other pests, often in combination with synergists such as piperonyl butoxide. Its rapid knockdown effect and relatively low mammalian toxicity make it widely used in pest control applications.
Yes, Tetramethrin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1788386. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 83975. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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