Thioridazine

CHEMBL479 Phase 4 Aprovado Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
370.6 g/mol
LogP
5.9
Phase
4

This older antipsychotic medication was used to treat schizophrenia and severe behavioral problems, but its use is now very restricted due to serious risks including irreversible damage to the retina of the eye and potentially fatal heart rhythm abnormalities. It works by blocking dopamine receptors in the brain. It is only considered when other antipsychotics have failed.

Peso Molecular

370,6000 g/mol

LogP

5,90

TPSA

57,10 Ų

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

CSc1ccc2c(c1)N(CCC1CCCCN1C)c1ccccc1S2

InChI

InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3

Molecular Formula

C21H26N2S2

HBD / HBA

- / 4

Ligações Rotacionáveis

4

Átomos Pesados

25

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This older antipsychotic medication was used to treat schizophrenia and severe behavioral problems, but its use is now very restricted due to serious risks including irreversible damage to the retina of the eye and potentially fatal heart rhythm abnormalities. It works by blocking dopamine receptors in the brain. It is only considered when other antipsychotics have failed.

Yes, Thioridazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL479. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 5452. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.