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Trimethadione

CHEMBL695 Phase 4 Aprovado Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
143.1 g/mol
LogP
0.3
Phase
4

This older anticonvulsant medication was used to treat absence seizures (petit mal epilepsy) that did not respond to other treatments. It works by reducing abnormal electrical activity in the brain. Due to serious toxicity risks including fetal harm, liver damage, and kidney problems, it has been largely replaced by safer medications and is rarely used today.

Peso Molecular

143,1400 g/mol

LogP

0,30

TPSA

46,60 Ų

Regra dos 5 de Lipinski

Aprovado

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

                    
CN1C(=O)OC(C)(C)C1=O

                

                

                
                

                    
InChI

                    
InChI=1S/C6H9NO3/c1-6(2)4(8)7(3)5(9)10-6/h1-3H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C6H9NO3

                    

                    
                    

                        
HBD / HBA

                        
- / 3

                    

                    
                    

                        
Ligações Rotacionáveis

                        
0

                    

                    
                    
                    

                        
Átomos Pesados

                        
10

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
This older anticonvulsant medication was used to treat absence seizures (petit mal epilepsy) that did not respond to other treatments. It works by reducing abnormal electrical activity in the brain. Due to serious toxicity risks including fetal harm, liver damage, and kidney problems, it has been largely replaced by safer medications and is rarely used today.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Trimethadione is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL695.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5576.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.