Tryptophan

CHEMBL54976 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

204.2 g/mol

LogP

-1.1

Phase

4

Tryptophan is an essential amino acid and the precursor for serotonin and melatonin biosynthesis, playing critical roles in mood regulation, sleep, and immune function through the serotonin-kynurenine metabolic pathways. It has been investigated as a dietary supplement and therapeutic agent for depression, insomnia, and anxiety, and tryptophan metabolism abnormalities are implicated in neurological conditions such as Alzheimer's disease. Its role as a serotonin precursor underlies research into mood and cognitive disorders.

Peso Molecular

204,2200 g/mol

LogP

-1,10

TPSA

79,10 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Benign Prostatic Hyperplasia Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Migraine Schizophrenia Bipolar Disorder Generalized Anxiety Disorder Melanoma Multiple Sclerosis Chronic Kidney Disease Obesity Type 2 Diabetes Hypertension Major Depressive Disorder Breast Cancer Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

InChI

InChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

Molecular Formula

C11H12N2O2

HBD / HBA

3 / 3

Ligações Rotacionáveis

3

Átomos Pesados

15

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Tryptophan is an essential amino acid and the precursor for serotonin and melatonin biosynthesis, playing critical roles in mood regulation, sleep, and immune function through the serotonin-kynurenine metabolic pathways. It has been investigated as a dietary supplement and therapeutic agent for depression, insomnia, and anxiety, and tryptophan metabolism abnormalities are implicated in neurological conditions such as Alzheimer's disease. Its role as a serotonin precursor underlies research into mood and cognitive disorders.

Yes, Tryptophan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL54976. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6305. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estrutura

Dados Rápidos

Fórmula: C11H12N2O2
Sinônimos: 28

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.