Varenicline
This prescription medication is used to help adults quit smoking by both reducing the pleasurable effects of cigarettes and relieving withdrawal symptoms. It works by partially stimulating and blocking nicotinic acetylcholine receptors in the brain that respond to nicotine. Some patients experience changes in mood or behavior during treatment, so any unusual thoughts or feelings should be reported to a doctor.
Peso Molecular
211,2600 g/mol
LogP
0,80
TPSA
37,80 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
c1cnc2cc3c(cc2n1)[C@@H]1CNC[C@H]3C1
InChI
InChI=1S/C13H13N3/c1-2-16-13-5-11-9-3-8(6-14-7-9)10(11)4-12(13)15-1/h1-2,4-5,8-9,14H,3,6-7H2/t8-,9+
Molecular Formula
C13H13N3
HBD / HBA
1 / 3
Ligações Rotacionáveis
0
Átomos Pesados
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
This prescription medication is used to help adults quit smoking by both reducing the pleasurable effects of cigarettes and relieving withdrawal symptoms. It works by partially stimulating and blocking nicotinic acetylcholine receptors in the brain that respond to nicotine. Some patients experience changes in mood or behavior during treatment, so any unusual thoughts or feelings should be reported to a doctor.
Yes, Varenicline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1076903. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5310966. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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