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Vibrio Cholerae, Live Attenuated

CHEMBL2108939 Phase 4 Aprovado Vaccine component
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
— g/mol
LogP
—
Phase
4

Live attenuated Vibrio cholerae strains, such as the CVD 103-HgR strain used in Vaxchora, are genetically modified to delete virulence genes while retaining immunogenicity, producing a single-dose oral vaccine against cholera. Oral ingestion of the attenuated strain stimulates robust intestinal mucosal immunity (IgA) and systemic immune responses against V. cholerae O1, providing protection for at-risk travelers. The live vaccine generates broader and more durable immunity than killed whole-cell vaccines.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Live attenuated Vibrio cholerae strains, such as the CVD 103-HgR strain used in Vaxchora, are genetically modified to delete virulence genes while retaining immunogenicity, producing a single-dose oral vaccine against cholera. Oral ingestion of the attenuated strain stimulates robust intestinal mucosal immunity (IgA) and systemic immune responses against V. cholerae O1, providing protection for at-risk travelers. The live vaccine generates broader and more durable immunity than killed whole-cell vaccines.

Yes, Vibrio Cholerae, Live Attenuated is an approved drug. It has reached clinical phase 4. It is classified as a Vaccine component.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2108939. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.