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Viomycin Sulfate

CHEMBL3989823 Phase 4 Aprovado Protein
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
783.8 g/mol
LogP
—
Phase
4

Viomycin sulfate is the sulfate salt of viomycin, a cyclic peptide antibiotic with antimycobacterial activity used as a second-line agent for drug-resistant tuberculosis. The sulfate salt form was used in parenteral formulations for intramuscular administration. Like the free base, it inhibits bacterial protein synthesis by targeting ribosomal translocation but causes significant nephrotoxicity and ototoxicity.

Peso Molecular

783,8000 g/mol

TPSA

476,00 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
NCCC[C@H](N)CC(=O)N[C@H]1CNC(=O)[C@H]([C@H]2C[C@H](O)NC(N)=N2)NC(=O)/C(=C/NC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC1=O.O=S(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C25H43N13O10.H2O4S/c26-3-1-2-10(27)4-16(41)32-12-6-30-23(47)18(11-5-17(42)37-24(28)36-11)38-20(44)13(7-31-25(29)48)33-21(45)14(8-39)35-22(46)15(9-40)34-19(12)43;1-5(2,3)4/h7,10-12,14-15,17-18,39-40,42H,1-6,8-9,26-27H2,(H,30,47)(H,32,41)(H,33,45)(H,34,43)(H,35,46)(H,38,44)(H3,28,36,37)(H3,29,31,48);(H2,1,2,3,4)/b13-7-;/t10-,11+,12-,14-,15-,17-,18-;/m0./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C25H45N13O14S

                    

                    
                    

                        
HBD / HBA

                        
17 / 17

                    

                    
                    

                        
Ligações Rotacionáveis

                        
10

                    

                    
                    
                    

                        
Átomos Pesados

                        
53

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Perguntas frequentes

                

                    
                    

                        
                        

                            
Viomycin sulfate is the sulfate salt of viomycin, a cyclic peptide antibiotic with antimycobacterial activity used as a second-line agent for drug-resistant tuberculosis. The sulfate salt form was used in parenteral formulations for intramuscular administration. Like the free base, it inhibits bacterial protein synthesis by targeting ribosomal translocation but causes significant nephrotoxicity and ototoxicity.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Viomycin Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3989823.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 135524783.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Aviso Médico

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.