Zonisamide

CHEMBL750 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

212.2 g/mol

LogP

0.2

Phase

4

This anticonvulsant medication is used as an add-on treatment for partial seizures in adults with epilepsy and is also used off-label as an adjunct in Parkinson's disease. It works through multiple mechanisms including blocking sodium and calcium channels in the brain to reduce abnormal electrical activity. It can cause kidney stones, so adequate hydration is important, and it should be avoided in patients with sulfonamide allergies.

Peso Molecular

212,2300 g/mol

LogP

0,20

TPSA

94,60 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Epilepsy Migraine Schizophrenia Bipolar Disorder Obesity Hypertension

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

NS(=O)(=O)Cc1noc2ccccc12

InChI

InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)

Molecular Formula

C8H8N2O3S

HBD / HBA

1 / 5

Ligações Rotacionáveis

2

Átomos Pesados

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

This anticonvulsant medication is used as an add-on treatment for partial seizures in adults with epilepsy and is also used off-label as an adjunct in Parkinson's disease. It works through multiple mechanisms including blocking sodium and calcium channels in the brain to reduce abnormal electrical activity. It can cause kidney stones, so adequate hydration is important, and it should be avoided in patients with sulfonamide allergies.

Yes, Zonisamide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL750. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5734. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estrutura

Dados Rápidos

Fórmula: C8H8N2O3S
Sinônimos: 2

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.