Buprenorphine vs Oxycodone

## Buprenorphine vs Oxycodone: Overview

This comparison examines the pharmacological differences between **Buprenorphine** and **Oxycodone**.

## Mechanism of Action

**Buprenorphine**: Partial mu-opioid receptor agonist and kappa antagonist with high receptor affinity.

**Oxycodone**: Semisynthetic mu-opioid receptor agonist.

## Pharmacokinetics

**Half-life**: Buprenorphine — 24-42 hours; Oxycodone — 3-5 hours.

## Chemical Properties

**Molecular Formula**: Buprenorphine — C29H41NO4; Oxycodone — C18H21NO4.

**Molecular Weight**: Buprenorphine — 467.6430 g/mol; Oxycodone — 315.3640 g/mol.

**Type**: Buprenorphine — Small molecule; Oxycodone — Small molecule.