Captopril vs Valsartan

## Captopril vs Valsartan: Overview

This comparison examines the pharmacological differences between **Captopril** and **Valsartan**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Valsartan**: Angiotensin II type 1 receptor blocker.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Valsartan — 6 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Valsartan — C24H29N5O3.

**Molecular Weight**: Captopril — 217.2850 g/mol; Valsartan — 435.5190 g/mol.

**Type**: Captopril — Small molecule; Valsartan — Small molecule.