Cephalexin vs Trimethoprim

## Cephalexin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Cephalexin** and **Trimethoprim**.

## Mechanism of Action

**Cephalexin**: First-generation cephalosporin inhibiting cell wall synthesis.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Cephalexin — 0.5-1.2 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Cephalexin — C16H17N3O4S; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Cephalexin — 347.3890 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Cephalexin — Small molecule; Trimethoprim — Small molecule.