Cetirizine vs Hydrochlorothiazide

## Cetirizine vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Cetirizine** and **Hydrochlorothiazide**.

## Mechanism of Action

**Cetirizine**: Second-generation H1 antihistamine.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Cetirizine — 6.5-10 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Cetirizine — C21H25ClN2O3; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Cetirizine — 388.8900 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Cetirizine — Small molecule; Hydrochlorothiazide — Small molecule.