Gabapentin vs Phenytoin

## Gabapentin vs Phenytoin: Overview

This comparison examines the pharmacological differences between **Gabapentin** and **Phenytoin**.

## Mechanism of Action

**Gabapentin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

## Pharmacokinetics

**Half-life**: Gabapentin — 5-7 hours; Phenytoin — 22 hours.

## Chemical Properties

**Molecular Formula**: Gabapentin — C9H17NO2; Phenytoin — C15H12N2O2.

**Molecular Weight**: Gabapentin — 171.2370 g/mol; Phenytoin — 252.2680 g/mol.

**Type**: Gabapentin — Small molecule; Phenytoin — Small molecule.