Capsaicin
The active compound in chili peppers used topically and in patch form to relieve pain associated with conditions including neuropathy, arthritis, and post-herpetic neuralgia. It works by initially stimulating and then desensitizing pain-sensing nerve fibers through depletion of substance P and transient TRPV1 receptor overstimulation. Initial burning or stinging at the application site is common.
Молекулярная масса
305,4000 g/mol
LogP
3,60
TPSA
58,60 Ų
Правило пяти Липинского
Соответствует
Терапевтические области
Механизм действия
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D Структура
Cite this structure
Embed this structure
SMILES
COc1cc(CNC(=O)CCCC/C=C/C(C)C)ccc1O
InChI
InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6+
Molecular Formula
C18H27NO3
HBD / HBA
2 / 3
Вращаемые Связи
9
Тяжёлые Атомы
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
The active compound in chili peppers used topically and in patch form to relieve pain associated with conditions including neuropathy, arthritis, and post-herpetic neuralgia. It works by initially stimulating and then desensitizing pain-sensing nerve fibers through depletion of substance P and transient TRPV1 receptor overstimulation. Initial burning or stinging at the application site is common.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Capsaicin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL294199. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 1548943. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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