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Potassium Oxybate

CHEMBL4594395 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
142.2 g/mol
LogP
—
Phase
4

Potassium oxybate is the potassium salt form of gamma-hydroxybutyrate (GHB), a naturally occurring CNS depressant that acts on GABA-B receptors and specific GHB receptors in the brain to promote slow-wave sleep and reduce daytime sleepiness and cataplexy. It is used as an alternative formulation of sodium oxybate for the treatment of narcolepsy, particularly to reduce the sodium burden in patients with hypertension or sodium-restricted diets.

Молекулярная масса

142,1900 g/mol

TPSA

60,40 Ų

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=C([O-])CCCO.[K+]

                

                

                
                

                    
InChI

                    
InChI=1S/C4H8O3.K/c5-3-1-2-4(6)7;/h5H,1-3H2,(H,6,7);/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C4H7KO3

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
Вращаемые Связи

                        
3

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
8

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Potassium oxybate is the potassium salt form of gamma-hydroxybutyrate (GHB), a naturally occurring CNS depressant that acts on GABA-B receptors and specific GHB receptors in the brain to promote slow-wave sleep and reduce daytime sleepiness and cataplexy. It is used as an alternative formulation of sodium oxybate for the treatment of narcolepsy, particularly to reduce the sodium burden in patients with hypertension or sodium-restricted diets.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Potassium Oxybate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL4594395.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23689651.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.