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Primaquine

CHEMBL506 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
259.4 g/mol
LogP
2.2
Phase
4

An antiparasitic medication used to treat and prevent certain types of malaria, particularly to eliminate the dormant liver stages of Plasmodium vivax and Plasmodium ovale that can cause the infection to relapse weeks or months later. Before taking it, patients must be tested for a genetic enzyme deficiency (G6PD) that can cause serious blood problems.

Молекулярная масса

259,3500 g/mol

LogP

2,20

TPSA

60,20 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Malaria

Механизм действия

Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Механизм

Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1cc(NC(C)CCCN)c2ncccc2c1

                

                

                
                

                    
InChI

                    
InChI=1S/C15H21N3O/c1-11(5-3-7-16)18-14-10-13(19-2)9-12-6-4-8-17-15(12)14/h4,6,8-11,18H,3,5,7,16H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H21N3O

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
Вращаемые Связи

                        
6

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
An antiparasitic medication used to treat and prevent certain types of malaria, particularly to eliminate the dormant liver stages of Plasmodium vivax and Plasmodium ovale that can cause the infection to relapse weeks or months later. Before taking it, patients must be tested for a genetic enzyme deficiency (G6PD) that can cause serious blood problems.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Primaquine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL506.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4908.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.