Rosuvastatin
A potent statin medication used to lower LDL cholesterol and triglycerides while raising HDL cholesterol, significantly reducing the risk of heart attack, stroke, and other cardiovascular events. It is generally well-tolerated and effective at low doses, making it one of the most widely prescribed cholesterol-lowering medications.
Молекулярная масса
481,5390 g/mol
LogP
1,60
TPSA
149,00 Ų
Правило пяти Липинского
Соответствует
Терапевтические области
Классы препаратов
Механизм действия
Competitive inhibitor of HMG-CoA reductase.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Competitive inhibitor of HMG-CoA reductase.
2D Структура
Cite this structure
Embed this structure
SMILES
CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1/C=C/[C@@H](O)C[C@@H](O)CC(=O)O
InChI
InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1
Molecular Formula
C22H28FN3O6S
HBD / HBA
3 / 10
Вращаемые Связи
10
Тяжёлые Атомы
33
Rosuvastatin increases warfarin plasma concentrations through inhibition of CYP2C9, potentially leading to supratherapeutic INR values.
Rosuvastatin and colchicine share BCRP transporter-mediated elimination; colchicine may weakly increase rosuvastatin exposure, and both carry myotoxic potential that could be additive.
No side effects recorded
Side effect data is not yet available for this drug.
Часто задаваемые вопросы
A potent statin medication used to lower LDL cholesterol and triglycerides while raising HDL cholesterol, significantly reducing the risk of heart attack, stroke, and other cardiovascular events. It is generally well-tolerated and effective at low doses, making it one of the most widely prescribed cholesterol-lowering medications.
Competitive inhibitor of HMG-CoA reductase.
Key pharmacokinetic parameters for Rosuvastatin: Half-life: 19 hours.
Yes, Rosuvastatin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
Same Drug Class
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1496. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 446157. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Медицинский отказ от ответственности
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="rosuvastatin"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/rosuvastatin/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/rosuvastatin/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/rosuvastatin/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="rosuvastatin"></drugfyi-drug>