💊 Препараты А-Я 🧬 Мишени 🛠 Инструменты 📚 Руководства
Все препараты Классы препаратов Терапевтические области Побочные Эффекты
Руководства Глоссарий Хронология
Сравнения Путешествия препаратов Группы лекарственных средств
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Sulfameter

CHEMBL1200359 Phase 4 Одобрено Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
280.3 g/mol
LogP
0.4
Phase
4

Sulfameter is a very long-acting sulfonamide antibiotic with a plasma half-life of approximately 150 hours, used historically once or twice weekly for urinary tract infections and prevention of recurrent rheumatic fever. Its prolonged half-life results from slow renal excretion and extensive plasma protein binding. Like all sulfonamides, it inhibits bacterial dihydropteroate synthase. Its very long half-life increases the risk of cumulative sulfonamide toxicity.

Молекулярная масса

280,3100 g/mol

LogP

0,40

TPSA

116,00 Ų

Правило пяти Липинского

Соответствует

Терапевтические области

Benign Prostatic Hyperplasia Ophthalmology Asthma Schizophrenia Generalized Anxiety Disorder Nephrology Gastroesophageal Reflux Disease Stroke Lymphoma Heart Failure Atrial Fibrillation Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Структура

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1

                

                

                
                

                    
InChI

                    
InChI=1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H12N4O3S

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
Вращаемые Связи

                        
4

                    

                    
                    
                    

                        
Тяжёлые Атомы

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Часто задаваемые вопросы

                

                    
                    

                        
                        

                            
Sulfameter is a very long-acting sulfonamide antibiotic with a plasma half-life of approximately 150 hours, used historically once or twice weekly for urinary tract infections and prevention of recurrent rheumatic fever. Its prolonged half-life results from slow renal excretion and extensive plasma protein binding. Like all sulfonamides, it inhibits bacterial dihydropteroate synthase. Its very long half-life increases the risk of cumulative sulfonamide toxicity.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfameter is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200359.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5326.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Медицинский отказ от ответственности

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.