Bioisostere
A chemical substituent or group that mimics the spatial, electronic, or pharmacological properties of another group. Used in medicinal chemistry to optimize drug properties while maintaining biological activity.
Примеры
- F replaces H
- Tetrazole replaces carboxylate
- Thiophene replaces phenyl
Знаете ли вы?
A chemical substituent or group that mimics the spatial, electronic, or pharmacological properties of another group. Used in medicinal chemistry to optimize drug properties while maintaining biological activity.