Half Maximal Inhibitory Concentration (IC50)

IC50
Pharmacodynamics

The concentration of an inhibitor required to reduce a biological process by 50%. Used for enzyme inhibitors, receptor antagonists, and cytotoxicity assays. Context-dependent and not directly comparable across assays.

Примеры

  • Statin IC50 for HMG-CoA reductase
  • Kinase inhibitor IC50 panels
  • Antimicrobial IC50

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The concentration of an inhibitor required to reduce a biological process by 50%. Used for enzyme inhibitors, receptor antagonists, and cytotoxicity assays. Context-dependent and not directly comparable across assays.