ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
G-protein coupled receptor (Gs) predominantly expressed in the heart.
Функция
Beta-1 selective blockers (metoprolol, bisoprolol) treat hypertension, heart failure, and arrhythmias.
Препараты, действующие на данную мишень
| Препарат | Действие | Первичный |
|---|---|---|
| Metoprolol | Antagonist | Да |
| Carvedilol | Antagonist | Да |
| Propranolol | Antagonist | Да |
| Diltiazem | Other | Да |
| Albuterol | Agonist | — |
| Digoxin | Other | — |
Related Targets
OPRM1 (Mu-Opioid Receptor)
OPRM1
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2