SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
ER-resident chaperone protein involved in neuroprotection and pain modulation.
Функция
Emerging target for neuropathic pain, depression, and neurodegenerative diseases.
Препараты, действующие на данную мишень
| Препарат | Действие | Первичный |
|---|---|---|
| Lithium Carbonate | Other | Да |
| Tamoxifen | Antagonist | — |
| Diphenhydramine | Binder | — |
| Pregabalin | Binder | — |
| Donepezil | Binder | — |
Related Targets
OPRM1 (Mu-Opioid Receptor)
OPRM1
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2