SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
ER-resident chaperone protein involved in neuroprotection and pain modulation.
Function
Emerging target for neuropathic pain, depression, and neurodegenerative diseases.
Drugs Acting on This Target
| Drug | Action | Primary |
|---|---|---|
| Lithium Carbonate | Other | Yes |
| Tamoxifen | Antagonist | — |
| Diphenhydramine | Binder | — |
| Pregabalin | Binder | — |
| Donepezil | Binder | — |
Related Targets
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
DRD2 (Dopamine D2 Receptor)
DRD2
HRH1 (Histamine H1 Receptor)
HRH1
HRH2 (Histamine H2 Receptor)
HRH2
OPRM1 (Mu-Opioid Receptor)
OPRM1