Histamine

CHEMBL90 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

111.2 g/mol

LogP

-0.7

Phase

4

This naturally occurring chemical messenger plays a central role in immune responses, allergic reactions, gastric acid secretion, and neurotransmission. As a therapeutic agent, histamine has been used in immunotherapy protocols and studied in combination treatments for melanoma and leukemia. Paradoxically, administering histamine can in some contexts modulate immune function beneficially.

น้ำหนักโมเลกุล

111.1500 g/mol

LogP

-0.70

TPSA

54.70 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Glaucoma Pain Management Non-Small Cell Lung Cancer Rheumatoid Arthritis Asthma Chronic Obstructive Pulmonary Disease Alzheimer's Disease Migraine Schizophrenia Bipolar Disorder Melanoma Gastroesophageal Reflux Disease Psoriasis Multiple Sclerosis Obesity Lymphoma Type 2 Diabetes Hypertension Breast Cancer Atopic Dermatitis Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

NCCc1c[nH]cn1

InChI

InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

Molecular Formula

C5H9N3

HBD / HBA

2 / 2

พันธะที่หมุนได้

2

อะตอมหนัก

8

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This naturally occurring chemical messenger plays a central role in immune responses, allergic reactions, gastric acid secretion, and neurotransmission. As a therapeutic agent, histamine has been used in immunotherapy protocols and studied in combination treatments for melanoma and leukemia. Paradoxically, administering histamine can in some contexts modulate immune function beneficially.

Yes, Histamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL90. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 774. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Histamine บน PillFYI

โครงสร้าง

ข้อมูลด่วน

สูตร: C5H9N3
คำพ้องความหมาย: 66

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.