Indacaterol

CHEMBL1095777 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
392.5 g/mol
LogP
3.3
Phase
4

This ultra-long-acting beta-2 agonist (LABA) bronchodilator is inhaled once daily for the maintenance treatment of COPD and asthma. It relaxes the smooth muscle surrounding the airways, improving airflow and reducing breathlessness throughout the day. It is used as a maintenance medication and does not provide rapid relief during an acute attack.

น้ำหนักโมเลกุล

392.5000 g/mol

LogP

3.30

TPSA

81.60 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

กลไกการออกฤทธิ์

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

กลไก

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

โครงสร้าง 2 มิติ

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SMILES

CCc1cc2c(cc1CC)CC(NC[C@H](O)c1ccc(O)c3[nH]c(=O)ccc13)C2

InChI

InChI=1S/C24H28N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1

Molecular Formula

C24H28N2O3

HBD / HBA

4 / 4

พันธะที่หมุนได้

6

อะตอมหนัก

29

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This ultra-long-acting beta-2 agonist (LABA) bronchodilator is inhaled once daily for the maintenance treatment of COPD and asthma. It relaxes the smooth muscle surrounding the airways, improving airflow and reducing breathlessness throughout the day. It is used as a maintenance medication and does not provide rapid relief during an acute attack.

Activates beta-2 adrenergic receptors on bronchial smooth muscle, stimulating adenylyl cyclase and increasing intracellular cAMP. This relaxes airway smooth muscle and produces bronchodilation.

Yes, Indacaterol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1095777. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 6918554. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

ข้อจำกัดความรับผิดชอบทางการแพทย์

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.