Irbesartan

CHEMBL1513 Phase 4 ได้รับการอนุมัติ Small molecule

Half-Life

11-15 hours

Bioavailability

—

Protein Binding

—

Molecular Weight

428.5 g/mol

LogP

4.1

Phase

4

This angiotensin II receptor blocker (ARB) is used to treat high blood pressure, heart failure, and kidney disease in patients with type 2 diabetes. It works by blocking the AT1 receptor for angiotensin II, causing blood vessels to relax and reducing aldosterone secretion. It is often used in patients who cannot tolerate ACE inhibitors due to cough.

น้ำหนักโมเลกุล

428.5320 g/mol

LogP

4.10

TPSA

87.10 Å²

Lipinski RO5

ผ่าน

ด้านการรักษา

Ovarian Cancer Cardiovascular Disease Chronic Kidney Disease Stroke Hyperlipidemia Obesity Type 2 Diabetes Hypertension Hepatitis C Heart Failure Atrial Fibrillation

หมวดหมู่ยา

C — C - Cardiovascular System

กลไกการออกฤทธิ์

Selective non-competitive angiotensin II type 1 receptor antagonist.

Pharmacokinetics (PK)

Half-Life 11-15 hours

Pharmacodynamics (PD)

กลไก

Selective non-competitive angiotensin II type 1 receptor antagonist.

โครงสร้าง 2 มิติ

SVG PNG

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SMILES

CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

InChI

InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)

Molecular Formula

C25H28N6O

HBD / HBA

1 / 5

พันธะที่หมุนได้

7

อะตอมหนัก

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

คำถามที่พบบ่อย

This angiotensin II receptor blocker (ARB) is used to treat high blood pressure, heart failure, and kidney disease in patients with type 2 diabetes. It works by blocking the AT1 receptor for angiotensin II, causing blood vessels to relax and reducing aldosterone secretion. It is often used in patients who cannot tolerate ACE inhibitors due to cough.

Selective non-competitive angiotensin II type 1 receptor antagonist.

Key pharmacokinetic parameters for Irbesartan: Half-life: 11-15 hours.

Yes, Irbesartan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

Related Drugs

Same Drug Class

Atorvastatin Small molecule Amlodipine Small molecule Lisinopril Small molecule Metoprolol Small molecule

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1513. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3749. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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โครงสร้าง

ข้อมูลด่วน

Class: C - Cardiovascular System
สูตร: C25H28N6O
คำพ้องความหมาย: 3

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.

Irbesartan

ด้านการรักษา

หมวดหมู่ยา

กลไกการออกฤทธิ์

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

Cite this structure

Embed this structure

No targets recorded

No interactions recorded

No side effects recorded

คำถามที่พบบ่อย

Related Drugs

Same Drug Class

References & Data Sources

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