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Piperazine

CHEMBL1412 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
86.1 g/mol
LogP
-1.5
Phase
4

Piperazine is an anthelmintic agent that acts by causing hyperpolarization of Ascaris and Enterobius worm muscle membranes through GABA-mimetic activity, producing flaccid paralysis of the parasite which is then expelled by normal intestinal peristalsis. It has been used for the treatment of roundworm (ascariasis) and pinworm (enterobiasis) infections, and certain piperazine derivatives have demonstrated anticancer activity in preclinical studies.

น้ำหนักโมเลกุล

86.1400 g/mol

LogP

-1.50

TPSA

24.10 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

Melanoma Obesity Breast Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C1CNCCN1

                

                

                
                

                    
InChI

                    
InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

                

                

                

                    
                    

                        
Molecular Formula

                        
C4H10N2

                    

                    
                    

                        
HBD / HBA

                        
2 / 2

                    

                    
                    

                        
พันธะที่หมุนได้

                        
0

                    

                    
                    
                    

                        
อะตอมหนัก

                        
6

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
Piperazine is an anthelmintic agent that acts by causing hyperpolarization of Ascaris and Enterobius worm muscle membranes through GABA-mimetic activity, producing flaccid paralysis of the parasite which is then expelled by normal intestinal peristalsis. It has been used for the treatment of roundworm (ascariasis) and pinworm (enterobiasis) infections, and certain piperazine derivatives have demonstrated anticancer activity in preclinical studies.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Piperazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1412.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4837.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.