Ritonavir
An antiretroviral drug originally used to treat HIV, now most commonly used at low doses as a pharmacokinetic booster to increase the blood levels of other protease inhibitors and antiviral drugs. By inhibiting the CYP3A4 enzyme, it slows the breakdown of companion drugs and allows them to be taken less frequently.
น้ำหนักโมเลกุล
720.9000 g/mol
LogP
6.00
TPSA
202.00 Ų
Lipinski RO5
ไม่ผ่าน
ด้านการรักษา
กลไกการออกฤทธิ์
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
โครงสร้าง 2 มิติ
Cite this structure
Embed this structure
SMILES
CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1
InChI
InChI=1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
Molecular Formula
C37H48N6O5S2
HBD / HBA
4 / 9
พันธะที่หมุนได้
18
อะตอมหนัก
50
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
คำถามที่พบบ่อย
An antiretroviral drug originally used to treat HIV, now most commonly used at low doses as a pharmacokinetic booster to increase the blood levels of other protease inhibitors and antiviral drugs. By inhibiting the CYP3A4 enzyme, it slows the breakdown of companion drugs and allows them to be taken less frequently.
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Yes, Ritonavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL163. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 392622. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
ข้อจำกัดความรับผิดชอบทางการแพทย์
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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