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Sulfamethoxypyridazine

CHEMBL268869 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
280.3 g/mol
LogP
0.3
Phase
4

Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic with a plasma half-life allowing once-daily or less frequent dosing, used historically for urinary tract infections, dermatitis herpetiformis, and Pneumocystis pneumonia prophylaxis. Its extended half-life is attributed to high plasma protein binding and slow renal tubular secretion. Like other sulfonamides, it inhibits bacterial dihydropteroate synthase.

น้ำหนักโมเลกุล

280.3100 g/mol

LogP

0.30

TPSA

116.00 Ų

Lipinski RO5

ผ่าน

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

                

                

                
                

                    
InChI

                    
InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

                

                

                

                    
                    

                        
Molecular Formula

                        
C11H12N4O3S

                    

                    
                    

                        
HBD / HBA

                        
2 / 7

                    

                    
                    

                        
พันธะที่หมุนได้

                        
4

                    

                    
                    
                    

                        
อะตอมหนัก

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic with a plasma half-life allowing once-daily or less frequent dosing, used historically for urinary tract infections, dermatitis herpetiformis, and Pneumocystis pneumonia prophylaxis. Its extended half-life is attributed to high plasma protein binding and slow renal tubular secretion. Like other sulfonamides, it inhibits bacterial dihydropteroate synthase.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sulfamethoxypyridazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL268869.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5330.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.