Sulfamethoxypyridazine

CHEMBL268869 Phase 4 Onaylandı Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

280.3 g/mol

LogP

0.3

Phase

4

Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic with a plasma half-life allowing once-daily or less frequent dosing, used historically for urinary tract infections, dermatitis herpetiformis, and Pneumocystis pneumonia prophylaxis. Its extended half-life is attributed to high plasma protein binding and slow renal tubular secretion. Like other sulfonamides, it inhibits bacterial dihydropteroate synthase.

Moleküler Ağırlık

280,3100 g/mol

LogP

0,30

TPSA

116,00 Å²

Lipinski RO5

Geçer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Yapı

SVG PNG

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SMILES

COc1ccc(NS(=O)(=O)c2ccc(N)cc2)nn1

InChI

InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

Molecular Formula

C11H12N4O3S

HBD / HBA

2 / 7

Döndürülebilir Bağlar

4

Ağır Atomlar

19

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Sıkça Sorulan Sorular

Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic with a plasma half-life allowing once-daily or less frequent dosing, used historically for urinary tract infections, dermatitis herpetiformis, and Pneumocystis pneumonia prophylaxis. Its extended half-life is attributed to high plasma protein binding and slow renal tubular secretion. Like other sulfonamides, it inhibits bacterial dihydropteroate synthase.

Yes, Sulfamethoxypyridazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL268869. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5330. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Formül: C11H12N4O3S

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.