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Tiotropium

CHEMBL1900528 Phase 4 ได้รับการอนุมัติ Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
392.5 g/mol
LogP
2.3
Phase
4

This long-acting bronchodilator is used once daily as a maintenance treatment for chronic obstructive pulmonary disease (COPD) and sometimes asthma, to keep the airways open and reduce breathlessness. It works by blocking muscarinic receptors in the airway smooth muscle, causing the airways to relax and widen. It is delivered via a special inhaler device and is not a rescue medication for sudden breathlessness.

น้ำหนักโมเลกุล

392.5000 g/mol

LogP

2.30

TPSA

116.00 Ų

Lipinski RO5

ผ่าน

ด้านการรักษา

Glaucoma Cardiovascular Disease Non-Small Cell Lung Cancer Asthma Chronic Obstructive Pulmonary Disease Obesity Tuberculosis Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

โครงสร้าง 2 มิติ

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C[N+]1(C)[C@@H]2C[C@@H](OC(=O)C(O)(c3cccs3)c3cccs3)C[C@H]1[C@@H]1O[C@@H]12

                

                

                
                

                    
InChI

                    
InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11-,12-,13+,16-,17+

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H22NO4S2+

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
พันธะที่หมุนได้

                        
5

                    

                    
                    
                    

                        
อะตอมหนัก

                        
26

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
คำถามที่พบบ่อย

                

                    
                    

                        
                        

                            
This long-acting bronchodilator is used once daily as a maintenance treatment for chronic obstructive pulmonary disease (COPD) and sometimes asthma, to keep the airways open and reduce breathlessness. It works by blocking muscarinic receptors in the airway smooth muscle, causing the airways to relax and widen. It is delivered via a special inhaler device and is not a rescue medication for sudden breathlessness.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Tiotropium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1900528.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5487427.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
ข้อจำกัดความรับผิดชอบทางการแพทย์

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.