Tachyphylaxis
Rapid decrease in drug response after repeated administration over a short period. Distinguished from tolerance by its acute onset. Often involves depletion of neurotransmitter stores.
ตัวอย่าง
- Indirect sympathomimetics (ephedrine)
- Nitrate tolerance
- Nicotine (acute)
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Rapid decrease in drug response after repeated administration over a short period. Distinguished from tolerance by its acute onset. Often involves depletion of neurotransmitter stores.