Trough Concentration (Cmin)
CminThe lowest plasma drug concentration reached just before the next scheduled dose (Cmin). Used for therapeutic drug monitoring of aminoglycosides, vancomycin, and immunosuppressants.
ตัวอย่าง
- Vancomycin trough 15-20 mg/L
- Tacrolimus trough monitoring
- Digoxin trough <2 ng/mL
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The lowest plasma drug concentration reached just before the next scheduled dose (Cmin). Used for therapeutic drug monitoring of aminoglycosides, vancomycin, and immunosuppressants.