Bupropion vs Paroxetine

## Bupropion vs Paroxetine: Overview

This comparison examines the pharmacological differences between **Bupropion** and **Paroxetine**.

## Mechanism of Action

**Bupropion**: Norepinephrine-dopamine reuptake inhibitor (NDRI).

**Paroxetine**: Potent selective serotonin reuptake inhibitor with additional muscarinic and NE reuptake inhibition.

## Pharmacokinetics

**Half-life**: Bupropion — 21 hours; Paroxetine — 21 hours.

## Chemical Properties

**Molecular Formula**: Bupropion — C13H18ClNO; Paroxetine — C19H20FNO3.

**Molecular Weight**: Bupropion — 239.7420 g/mol; Paroxetine — 329.3730 g/mol.

**Type**: Bupropion — Small molecule; Paroxetine — Small molecule.