Cyclosporine vs Trimethoprim

## Cyclosporine vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Cyclosporine** and **Trimethoprim**.

## Mechanism of Action

**Cyclosporine**: Calcineurin inhibitor suppressing T-cell activation.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Cyclosporine — 6-12 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Cyclosporine — C62H111N11O12; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Cyclosporine — 1202.6100 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Cyclosporine — Protein; Trimethoprim — Small molecule.