Betamethasone
A potent synthetic corticosteroid that reduces inflammation and suppresses the immune system, used to treat a wide range of conditions including severe allergies, skin disorders, and inflammatory diseases. It is available in many formulations including creams, injections, and tablets. Long-term use carries risks of adrenal suppression and other systemic effects.
Moleküler Ağırlık
392,5000 g/mol
LogP
1,90
TPSA
94,80 Ų
Lipinski RO5
Geçer
Terapötik Alanlar
Etki Mekanizması
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
2D Yapı
Cite this structure
Embed this structure
SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InChI
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
Molecular Formula
C22H29FO5
HBD / HBA
3 / 6
Döndürülebilir Bağlar
2
Ağır Atomlar
28
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
A potent synthetic corticosteroid that reduces inflammation and suppresses the immune system, used to treat a wide range of conditions including severe allergies, skin disorders, and inflammatory diseases. It is available in many formulations including creams, injections, and tablets. Long-term use carries risks of adrenal suppression and other systemic effects.
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.
Yes, Betamethasone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL632. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9782. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="betamethasone"></div>Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/betamethasone/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/betamethasone/Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/betamethasone/)Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="betamethasone"></drugfyi-drug>